NVS-SM2 [CAS 1562333-92-9]
Partner: MedChemexpress LLC
| CAS No: | 1562333-92-9 |
| Applications: | Neuroscience-Neuromodulation |
| MW: | 406.52 |
| Formula: | C23H30N6O |
| SMILES: | OC1=C(C(N=N2)=CC=C2N(C(CC3(C)C)CC(C)(N3)C)C)C=CC(C4=CNN=C4)=C1 |
| Purity: | 99.00 |
| Description: | NVS-SM2 is a potent, orally active and brain-penetrant SMN2 splicing enhancer with an EC50 of 2 nM for SMN. NVS-SM2 enhances U1-pre-mRNA association. NVS-SM2 promotes exon 7 inclusion and restores normal survival motor neuron (SMN) protein expression. NVS-SM2 can be used for spinal muscular atrophy (SMA) research[1][2]. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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