Data Sheet

MSDS

ABT-384 [CAS 868623-40-9]

CAS No:	868623-40-9
Applications:	Metabolism-sugar/lipid metabolism
MW:	493.56
Formula:	C₂₅H₃₄F₃N₅O₂
SMILES:	NC([C@]12C[C@@H](C3)C(NC(C(C)(N4CCN(C5=CC=C(C(F)(F)F)C=N5)CC4)C)=O)[C@@H](C[C@@H]3C2)C1)=O
Purity:	99.94
Description:	ABT-384 is a potent, selective 11-?-hydroxysteroid dehydrogenase type 1 (11?-HSD1) inhibitor. ABT-384 exhibits high affinity (Ki 0.1-2.7 nM) against rodent, monkey, and human 11?-HSD1. ABT-384 blocks regeneration of active cortisol. ABT-384 can be used for the research of Alzheimer�s disease (AD)[1][2].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only