Data Sheet

MSDS

NVS-CECR2-1 [CAS 1992047-61-6]

CAS No:	1992047-61-6
Applications:	Cancer-programmed cell death
MW:	495.68
Formula:	C₂₇H₃₇N₅O₂S
SMILES:	CC1(C)CC(N2C=CC3=C2C=CC(C4=CC(NC5CC5)=NC(S(=O)(CCC)=O)=N4)=C3)CC(C)(C)N1
Purity:	99.40
Description:	NVS-CECR2-1, a non-BET family Bromodomain (BRD) inhibitor, is a potent and selective cat eye syndrome chromosome region, candidate 2 (CECR2) inhibitor. NVS-CECR2-1 binds to CECR2 BRD with high affinity (IC50=47 nM; KD=80 nM). NVS-CECR2-1 exhibits cytotoxic activity and induces apoptosis against various cancer cells by targeting CECR2 as well as via CECR2-independent mechanism[1].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only