Data Sheet

MSDS

GN44028 [CAS 1421448-26-1]

CAS No:	1421448-26-1
Applications:	Neuroscience-Neurodegeneration
MW:	305.33
Formula:	C₁₈H₁₅N₃O₂
SMILES:	C1(NC2=CC=C(OCCO3)C3=C2)=NNC4=C1CC5=CC=CC=C45
Purity:	99.37
Description:	GN44028 is a potent and orally active hypoxia inducible factor (HIF)-1? inhibitor, with an IC50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1? transcriptional activity without suppressing HIF-1? mRNA expression, HIF-1? protein accumulation, or HIF-1?/HIF-1? heterodimerization. GN44028 can be used in the research of cancers[1][3].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only