(R)-Gyramide A (hydrochloride) [CAS 1793050-70-0]
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| CAS No: | 1793050-70-0 |
| MW: | 442.98 |
| Formula: | C21H28ClFN2O3S |
| SMILES: | O=S(C1=CC(F)=CC=C1C)(N[C@H]2CN(CC3=CC=C(OC(C)C)C=C3)CC2)=O.[H]Cl |
| Description: | (R)-Gyramide A hydrochloride is a bacterial DNA gyrase inhibitor that disrupts supercoiling activity with an IC50 value of 3.3 �M. (R)-Gyramide A hydrochloride demonstrates antibacterial activity against E. coli, P. aeruginosa, and S. enterica (MICs of 10-80 �M). (R)-Gyramide A hydrochloride does not affect the closely related enzyme topoisomerase IV. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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