Data Sheet

MSDS

Tolebrutinib [CAS 1971920-73-6]

CAS No:	1971920-73-6
Applications:	Cancer-Kinase/protease
MW:	455.51
Formula:	C₂₆H₂₅N₅O₃
SMILES:	O=C(N1[C@H]2CN(C(C=C)=O)CCC2)N(C3=CC=C(OC4=CC=CC=C4)C=C3)C5=C1C=CN=C5N
Purity:	98.96
Description:	Tolebrutinib (SAR442168) is a potent, selective, orally active and brain-penetrant inhibitor of Bruton tyrosine kinase (BTK), with IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively. Tolebrutinib exhibits efficacy in central nervous system immunity. Tolebrutinib can be used for the research of multiple sclerosis (MS)[1][2].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only