Data Sheet

MSDS

Famitinib [CAS 1044040-56-3]

CAS No:	1044040-56-3
Applications:	Cancer-Kinase/protease
MW:	410.48
Formula:	C₂₃H₂₇FN₄O₂
SMILES:	O=C1C2=C(NC(/C=C3C(NC4=C\3C=C(F)C=C4)=O)=C2C)CCN1CCN(CC)CC
Purity:	98.43
Description:	Famitinib (SHR1020), an orally active multi-targeted kinase inhibitor, inhibits the activity of c-kit, VEGFR-2 and PDGFR? with IC50 values of 2.3 nM, 4.7 nM and 6.6 nM, respectively[1]. Famitinib exerts powerful antitumor activity in human gastric cancer cells and xenografts. Famitinib triggers apoptosis[2].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only