Data Sheet

MSDS

Almorexant (hydrochloride) [CAS 913358-93-7]

CAS No:	913358-93-7
Applications:	Neuroscience-Neuromodulation
MW:	549.02
Formula:	C₂₉H₃₂ClF₃N₂O₃
SMILES:	CNC([C@@H](C1=CC=CC=C1)N2CCC3=CC(OC)=C(OC)C=C3[C@@H]2CCC4=CC=C(C(F)(F)F)C=C4)=O.Cl
Purity:	99.98
Description:	Almorexant (ACT 078573) hydrochloride is an orally active, potent and competitive dual orexin receptor antagonist, with Kd values of 1.3 nM (OX1) and 0.17 nM (OX2), respectively. Almorexant hydrochloride reversibly blocks signaling of orexin-A and orexin-B peptides. Almorexant hydrochloride totally blocked the intracellular Ca2+ signal pathway. Almorexant hydrochloride stimulates caspase-3 activity in AsPC-1 cells and induces apoptosis[1][2][3][4].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only