Data Sheet

MSDS

Almorexant [CAS 871224-64-5]

CAS No:	871224-64-5
Applications:	Neuroscience-Neuromodulation
MW:	512.56
Formula:	C₂₉H₃₁F₃N₂O₃
SMILES:	CNC([C@@H](C1=CC=CC=C1)N2CCC3=CC(OC)=C(OC)C=C3[C@@H]2CCC4=CC=C(C(F)(F)F)C=C4)=O
Purity:	99.71
Description:	Almorexant (ACT 078573) is an orally active, potent and competitive dual orexin receptor antagonist, with Kd values of 1.3 nM (OX1) and 0.17 nM (OX2), respectively. Almorexant reversibly blocks signaling of orexin-A and orexin-B peptides. Almorexant totally blocked the intracellular Ca2+ signal pathway. Almorexant stimulates caspase-3 activity in AsPC-1 cells and induces apoptosis[1][2][3][4].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only