(�)-J-113397 [CAS 217461-40-0]
Partner: MedChemexpress LLC
CAS No: | 217461-40-0 |
Applications: | Neuroscience-Neuromodulation |
MW: | 399.57 |
Formula: | C24H37N3O2 |
SMILES: | O=C1N([C@](CCN2CC3CCCCCCC3)([H])[C@H](C2)CO)C4=CC=CC=C4N1CC |
Purity: | 98.59 |
Description: | (�)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist with a Ki of 1.8 nM for cloned human ORL1. J-113397 inhibited nociceptin/orphanin FQ-stimulated GTP?S binding to CHO cells expressing ORL1 with an IC50 value of 5.3 nM. J-113397 can be used for researching the physiological roles of nociceptin/orphanin FQ[1]. |
Shipping Conditions: | Ship at ambient |
Usage: | Research Use Only |
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