VU-29 [CAS 890764-36-0] (10mM in DMSO)
Partner: MedChemexpress LLC
CAS No: | 890764-36-0 |
Applications: | Neuroscience-Neurodegeneration |
MW: | 384.39 |
Formula: | C22H16N4O3 |
SMILES: | O=C(NC1=CC(C2=CC=CC=C2)=NN1C3=CC=CC=C3)C4=CC=C([N+]([O-])=O)C=C4 |
Purity: | 99.63 |
Description: | VU-29 is a positive allosteric modulator of metabotropic glutamate 5 (mGlu5) receptor (EC50=9 nM and Ki=244 nM for rmGluR5). VU-29 is selective for mGluR5 relative to other mGluR subtypes (EC50: rmGluR1/rmGluR2=557 nM/1.5 ?M; hmGluR4=154 nM)[1][2]. |
Shipping Conditions: | Ship on cold packs |
Usage: | Research Use Only |
Insight Biotechnology Ltd reserves the right to change pricing without notice