Data Sheet

MSDS

SC75741 [CAS 913822-46-5]

CAS No:	913822-46-5
Applications:	COVID-19-anti-virus
MW:	565.67
Formula:	C₂₉H₂₃N₇O₂S₂
SMILES:	O=C(NC1=NC(C=CC(C(C2=CC=CC=C2)=O)=C3)=C3N1)C4=CSC(C(CC5)CCN5C6=NC=NC7=C6SC=C7)=N4
Purity:	99.51
Description:	SC75741 is a broad and efficient NF-?B inhibitor with an IC50 of 200 nM for p65[1]. SC75741 blocks influenza viruses (IV) replication. SC75741 impairs DNA binding of the NF-?B subunit p65, resulting in reduced expression of cytokines, chemokines, and pro-apoptotic factors. SC75741 subsequently inhibits caspase activation and blocks caspase-mediated nuclear export of viral ribonucleoproteins[2].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only