Data Sheet

MSDS

1A-116 [CAS 1430208-73-3]

CAS No:	1430208-73-3
Applications:	Cancer-Kinase/protease
MW:	307.31
Formula:	C₁₆H₁₆F₃N₃
SMILES:	N=C(NC1=CC=CC=C1C(F)(F)F)NC2=CC(C)=CC(C)=C2
Purity:	99.79
Description:	1A-116, a potent Rac1 inhibitor, is specific for W56 residues, can prevent EGF-induced Rac1 activation and block Rac1-P-Rex1 interaction. 1A-116 can induce apoptosis and inhibit cell proliferation, migration and cycle progression in a concentration-dependent manner. 1A-116 also demonstrates a high antimetastatic activity in vivo[1][2][3].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only