GW779439X [CAS 551919-98-3]
Partner: MedChemexpress LLC
| CAS No: | 551919-98-3 |
| Applications: | COVID-19-anti-virus |
| MW: | 454.45 |
| Formula: | C22H21F3N8 |
| SMILES: | FC(C1=CC(NC2=NC=CC(C3=C4C=CC=NN4N=C3)=N2)=CC=C1N5CCN(C)CC5)(F)F |
| Purity: | 99.85 |
| Description: | GW779439X is a pyrazolopyridazine identified in an inhibitor of the S. aureus PASTA kinase Stk1. GW779439X potentiates the activity of ?-lactam antibiotics against various MRSA and MSSA isolates, some even crossing the breakpoint from resistant to sensitive. GW779439X is an AURKA inhibitor and induces apoptosis by the caspases 3/7 pathway[1][2]. MRSA:methicillin-resistant S. aureus; MSSA: methicillin-sensitive S. aureus |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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