Data Sheet

MSDS

DuP-697 [CAS 88149-94-4]

CAS No:	88149-94-4
Applications:	COVID-19-immunoregulation
MW:	411.31
Formula:	C₁₇H₁₂BrFO₂S₂
SMILES:	O=S(C1=CC=C(C2=C(C3=CC=C(F)C=C3)SC(Br)=C2)C=C1)(C)=O
Purity:	99.0
Description:	DuP-697 is a member of the vicinal diaryl heterocycles and a potent, irreversible, selective and orally active COX-2 inhibitor (IC50 of 10 nM and 800 nM for human COX-2 and COX-1, respectively). DuP-697 exerts antiproliferative (IC50 of 42.8 nM), antiangiogenic and apoptotic effects on HT29 colorectal cancer cells. DuP-697 inhibits prostaglandin synthesis and has anti-inflammatory, anticancer and antipyretic effects[1][2][3].
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only