Antalarmin (hydrochloride) [CAS 220953-69-5]
Partner: MedChemexpress LLC
| CAS No: | 220953-69-5 |
| Applications: | Metabolism-protein/nucleotide metabolism |
| MW: | 415.01 |
| Formula: | C24H35ClN4 |
| SMILES: | CC1=C(N2C(C)=C(C)C3=C(N(CCCC)CC)N=C(C)N=C32)C(C)=CC(C)=C1.[H]Cl |
| Purity: | 99.68 |
| Description: | Antalarmin (hydrochloride) is a non-peptide corticotropin-releasing hormone receptor 1 (CRHR1) antagonist with a Ki of 1 nM. Antalarmin hydrochloride suppresses CRH-induced ACTH secretion and blocks CRH and novelty induced anxiety-like behavior in animal models. Antalarmin hydrochloride produces anti-inflammatory effects in arthritis models, and suppresses stress-induced gastric ulceration related to irritable bowel syndrome[1][2][3]. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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