(1R,2R)-Calhex 231 (hydrochloride)
Partner: MedChemexpress LLC
| MW: | 443.41 |
| Formula: | C25H28Cl2N2O |
| SMILES: | O=C(N[C@H]1[C@H](N[C@@H](C2=C3C=CC=CC3=CC=C2)C)CCCC1)C4=CC=C(Cl)C=C4.[H]Cl |
| Purity: | 99.07 |
| Description: | (1R,2R)-Calhex 231 hydrochloride is the inactive isomer of Calhex 231 hydrochloride (HY-103320A), and can be used as an experimental control. Calhex 231 hydrochloride is a CaSR inhibitor via negative allosteric modulation. Calhex 231 hydrochloride blocks Ca2+-induced accumulation of [3H]inositol phosphate with an IC50 of 0.39 ?M in HEK293 cells. Calhex 231 hydrochloride has the potential for diabetic cardiomyopathy (DCM) treatment[1][2]. |
| Shipping Conditions: | Ship on cold packs |
| Usage: | Research Use Only |
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