Data Sheet

MSDS

Xestospongin C [CAS 88903-69-9]

CAS No:	88903-69-9
Applications:	Neuroscience-Neurodegeneration
MW:	446.71
Formula:	C₂₈H₅₀N₂O₂
SMILES:	[H][C@]1([C@](CCCCCC[C@@](CCN2CCC3)([H])O[C@@]2([H])[C@]3([H])CCCCCC4)([H])CCC5)N5CC[C@]4([H])O1
Purity:	90.0
Description:	Xestospongin C ((-)-Xestospongin C) is a selective, reversible inositol 1,4,5-trisphosphate receptor (IP3R) inhibitor. Xestospongin C acts as an inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) pump of internal stores. Xestospongin C blocks IP3-induced Ca2+ release from cerebellar microsomes with an IC50 of 358 nM. Xestospongin C is a valuable tool for investigating the structure and function of IP3Rs and Ca2+ signaling in neuronal and nonneuronal cells[1][2][3].
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only