Data Sheet

MSDS

Toceranib (phosphate) [CAS 874819-74-6]

CAS No:	874819-74-6
Applications:	Cancer-Kinase/protease
MW:	494.45
Formula:	C₂₂H₂₈FN₄O₆P
SMILES:	O=C(NCCN1CCCC1)C2=C(NC(/C=C3C(NC4=C\3C=C(C=C4)F)=O)=C2C)C.O=P(O)(O)O
Purity:	98.54
Description:	Toceranib phosphate (SU11654 phosphate) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR, VEGFR, and Kit with Kis of 5 and 6 nM for PDGFR? and Flk-1/KDR, respectively. Toceranib phosphate (SU11654 phosphate) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors[1] [2].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only