Data Sheet

MSDS

Toceranib [CAS 356068-94-5]

CAS No:	356068-94-5
Applications:	Cancer-Kinase/protease
MW:	396.46
Formula:	C₂₂H₂₅FN₄O₂
SMILES:	O=C(NCCN1CCCC1)C2=C(NC(/C=C3C(NC4=C\3C=C(C=C4)F)=O)=C2C)C
Purity:	96.86
Description:	Toceranib phosphate (SU11654 phosphate) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibits PDGFR, VEGFR, and Kit with Kis of 5 and 6 nM for PDGFR? and Flk-1/KDR, respectively. Toceranib phosphate (SU11654 phosphate) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors[1][2].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only