Adezmapimod (hydrochloride) [CAS 869185-85-3]
Partner: MedChemexpress LLC
| CAS No: | 869185-85-3 |
| Applications: | COVID-19-immunoregulation |
| MW: | 413.90 |
| Formula: | C21H17ClFN3OS |
| SMILES: | O=S(C1=CC=C(C2=NC(C3=CC=C(F)C=C3)=C(C4=CC=NC=C4)N2)C=C1)C.[H]Cl |
| Purity: | 99.71 |
| Description: | Adezmapimod (SB 203580) hydrochloride is a selective and ATP-competitive p38 MAPK inhibitor with IC50s of 50 nM and 500 nM for SAPK2a/p38 and SAPK2b/p38?2, respectively. Adezmapimod hydrochloride inhibits LCK, GSK3? and PKB? with IC50s of 100-500-fold higher than that for SAPK2a/p38. Adezmapimod hydrochloride is an autophagy and mitophagy activator[1]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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