Mirdametinib [CAS 391210-10-9]
Partner: MedChemexpress LLC
| CAS No: | 391210-10-9 |
| Applications: | Cancer-Kinase/protease |
| MW: | 482.19 |
| Formula: | C16H14F3IN2O4 |
| SMILES: | O=C(C1=CC=C(C(F)=C1NC2=CC=C(I)C=C2F)F)NOC[C@H](O)CO |
| Purity: | 99.95 |
| Description: | Mirdametinib (PD0325901) is an orally active, selective and non-ATP-competitive MEK inhibitor with an IC50 of 0.33 nM. Mirdametinib exhibits a Kiapp of 1 nM against activated MEK1 and MEK2. Mirdametinib suppresses the expression of p-ERK1/2 and induces apoptosis. Mirdametinib has anti-cancer activity for a broad spectrum of human tumor xenografts[1][2][3]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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