Data Sheet

MSDS

BMS-309403 [CAS 300657-03-8]

CAS No:	300657-03-8
Applications:	COVID-19-immunoregulation
MW:	474.55
Formula:	C₃₁H₂₆N₂O₃
SMILES:	O=C(O)COC1=CC(C2=CC=CC=C2N3N=C(C4=CC=CC=C4)C(C5=CC=CC=C5)=C3CC)=CC=C1
Purity:	99.91
Description:	BMS-309403 is a potent, orally active and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor with Kis of <2, 250, and 350 nM for FABP4, FABP3, and FABP5, respectively. BMS-309403 interacts with the fatty-acid-binding pocket within the interior of the protein and competitively inhibits the binding of endogenous fatty acids. BMS-309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells[1][2][3].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only