NPS-2143 (hydrochloride) [CAS 324523-20-8]
Partner: MedChemexpress LLC
| CAS No: | 324523-20-8 |
| Applications: | Metabolism-protein/nucleotide metabolism |
| MW: | 445.38 |
| Formula: | C24H26Cl2N2O2 |
| SMILES: | N#CC1=C(OC[C@@H](CNC(C)(C)CC2=CC=C3C=CC=CC3=C2)O)C=CC=C1Cl.[H]Cl |
| Purity: | 99.80 |
| Description: | NPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 hydrochloride (SB-262470A hydrochloride) blocks increases in cytoplasmic Ca2+ concentrations (IC50=43 nM) elicited by activating the Ca2+ receptor in HEK 293 cells expressing the human Ca2+ receptor[1][2]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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