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Cat Number:	HY-101042-100mg
Size:	100mg
Price:	£473.00
Quantity:
Shipping:	£12.00

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Data Sheet

MSDS

AG-494 [CAS 133550-35-3]

Partner: MedChemexpress LLC

CAS No:	133550-35-3
Applications:	COVID-19-immunoregulation
MW:	280.28
Formula:	C₁₆H₁₂N₂O₃
SMILES:	O=C(NC1=CC=CC=C1)/C(C#N)=C/C2=CC=C(O)C(O)=C2
Purity:	99.31
Description:	AG-494 (Tyrphostin AG 494) is a potent and selective EGFR tyrosine kinase inhibitor (IC50=0.7 ?M). AG-494 inhibits the autophosphorylation of EGFR, ErbB2, HER1-2 and PDGF-R with IC50s 1.1, 39, 45 and 6 ?M, respectively. AG-494 blocks Cdk2 activation and inhibits EGF-dependent DNA synthesis[1][2][3].
Shipping Conditions:	Ship at ambient
Usage:	Research Use Only

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