SIS3 (free base) [CAS 521985-36-4]
Partner: MedChemexpress LLC
CAS No: | 521985-36-4 |
Applications: | COVID-19-immunoregulation |
MW: | 453.53 |
Formula: | C28H27N3O3 |
SMILES: | O=C(/C=C/C1=C(N(C2=NC=CC=C21)C)C3=CC=CC=C3)N4CC5=C(CC4)C=C(C(OC)=C5)OC |
Purity: | 98.11 |
Description: | SIS3 free base is a potent and selective inhibitor of Smad3 phosphorylation. SIS3 free base inhibits the myofibroblast differentiation of fibroblasts by TGF-?1. SIS3 free base does not affect the phosphorylation of Smad2[1]. |
Shipping Conditions: | Ship at ambient |
Usage: | Research Use Only |
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