CNX-500 [CAS 1202758-21-1]
Partner: MedChemexpress LLC
| CAS No: | 1202758-21-1 |
| Applications: | Cancer-Kinase/protease |
| MW: | 961.18 |
| Formula: | C48H68N10O9S |
| SMILES: | O=C(NCCCOCCOCCOCCCNC(CCCC[C@@H]1SC[C@]([C@]1([H])N2)([H])NC2=O)=O)CCCC(NCCCOC3=CC=CC(NC4=NC=C(C)C(NC5=CC=CC(NC(C=C)=O)=C5)=N4)=C3)=O |
| Purity: | 99.88 |
| Description: | CNX-500 is a probe consisting of a covalent Btk inhibitor (CC-292) chemically linked to biotin. CNX-500 retains inhibitory activity against Btk (IC50 of 0.5 nM) and the ability to form a covalent bond with Btk. CNX-500 has low inhibitory effects on kinase epidermal growth factor receptor, and upstream Src-family kinases including Syk and Lyn[1]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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