Data Sheet

MSDS

RSL3 [CAS 1219810-16-8] (10mM in DMSO)

CAS No:	1219810-16-8
Applications:	Cancer-programmed cell death
MW:	440.88
Formula:	C₂₃H₂₁ClN₂O₅
SMILES:	O=C([C@H]1CC2=C([C@H](C3=CC=C(C(OC)=O)C=C3)N1C(CCl)=O)NC4=C2C=CC=C4)OC
Purity:	99.90
Description:	RSL3 ((1S,3R)-RSL3) is an inhibitor of glutathione peroxidase 4 (GPX4) (ferroptosis activator), reduces the expression of GPX4 protein, and induces ferroptotic death of head and neck cancer cell. RSL3 increases the expression of p62 and Nrf2 and inactivates Keap1 in HN3-rslR cells[1].
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only