DM1-SMe [CAS 138148-68-2]
Partner: MedChemexpress LLC
| CAS No: | 138148-68-2 |
| Applications: | Cancer-programmed cell death |
| MW: | 784.38 |
| Formula: | C36H50ClN3O10S2 |
| SMILES: | C[C@]12[C@@]([C@@H]([C@]3([H])C[C@]([C@@H](/C=C/C=C(CC4=CC(N(C(C[C@@H]2OC([C@H](C)N(C)C(CCSSC)=O)=O)=O)C)=C(C(OC)=C4)Cl)\C)OC)(NC(O3)=O)O)C)([H])O1 |
| Purity: | 98.02 |
| Description: | DM1-SMe is an unconjugated form of the Maytansinoid in IMGN901. DM1-SMe is about 3-10-fold more potent than the parent agent Maytansine, with IC50s ranging from 0.003 to 0.01 nM for DM1-SMe in a panel of human tumor cell lines[1]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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