O-Desmethyl gefitinib [CAS 847949-49-9]
Partner: MedChemexpress LLC
| CAS No: | 847949-49-9 |
| Applications: | Cancer-Kinase/protease |
| MW: | 432.88 |
| Formula: | C21H22ClFN4O3 |
| SMILES: | OC1=CC2=NC=NC(NC3=CC=C(F)C(Cl)=C3)=C2C=C1OCCCN4CCOCC4 |
| Purity: | 99.40 |
| Description: | O-Desmethyl gefitinib is an active metabolite of Gefitinib in human plasma. The formation of O-desmethyl gefitinib is dependent on CYP2D6 activity. O-desmethyl gefitinib inhibits EGFR with an IC50 of 36 nM in subcellular assays[1][2]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
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