PT-262 [CAS 86811-36-1]
Partner: MedChemexpress LLC
CAS No: | 86811-36-1 |
Applications: | Cancer-Kinase/protease |
MW: | 276.72 |
Formula: | C14H13ClN2O2 |
SMILES: | O=C(C(N1CCCCC1)=C2Cl)C3=C(N=CC=C3)C2=O |
Purity: | 99.21 |
Description: | PT-262 is a potent ROCK inhibitor with an IC50 value of around 5 μM. PT-262 induces the loss of mitochondrial membrane potential and elevates the caspase-3 activation and apoptosis. PT-262 inhibits the ERK and CDC2 phosphorylation via a p53-independent pathway. PT-262 blocks cytoskeleton function and cell migration. PT-262 has anti-cancer activity[1][2]. |
Shipping Conditions: | Ship at ambient |
Usage: | Research Use Only |
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