PT-262 [CAS 86811-36-1]
Partner: MedChemexpress LLC
| CAS No: | 86811-36-1 |
| Applications: | Cancer-Kinase/protease |
| MW: | 276.72 |
| Formula: | C14H13ClN2O2 |
| SMILES: | O=C(C(N1CCCCC1)=C2Cl)C3=C(N=CC=C3)C2=O |
| Purity: | 99.21 |
| Description: | PT-262 is a potent ROCK inhibitor with an IC50 value of around 5 ?M. PT-262 induces the loss of mitochondrial membrane potential and elevates the caspase-3 activation and apoptosis. PT-262 inhibits the ERK and CDC2 phosphorylation via a p53-independent pathway. PT-262 blocks cytoskeleton function and cell migration. PT-262 has anti-cancer activity[1][2]. |
| Shipping Conditions: | Ship at ambient |
| Usage: | Research Use Only |
Insight Biotechnology Ltd reserves the right to change pricing without notice
