Data Sheet

MSDS

Vonoprazan [CAS 881681-00-1] (10mM in DMSO)

CAS No:	881681-00-1
MW:	345.39
Formula:	C₁₇H₁₆FN₃O₂S
SMILES:	O=S(N1C=C(CNC)C=C1C2=CC=CC=C2F)(C3=CC=CN=C3)=O
Purity:	99.89
Description:	Vonoprazan (TAK-438 free base), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. Vonoprazan inhibits H+,K+-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan is developed for the research of acid-related diseases, such as gastroesophageal reflux disease and peptic ulcer disease. Vonoprazan can be used for eradication of Helicobacter pylori[1][2][3].
Shipping Conditions:	Ship on cold packs
Usage:	Research Use Only