Ordering Details
Cat Number:	GTX33911
Size:	100ug
Concentration:	1mg/mL
Price:	£544.00
Quantity:
Shipping:	£12.00

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Data Sheet

ADAM17 [D1(A12)] (Azide free), Human Monoclonal Antibody

Partner: GeneTex International Corporation

Applications:	Functional Assay
Species Reactivity:	Human
Isotype:	Human IgG1
Purification:	Protein A/G-affinity purified.
Conjugation:	Unconjugated
MW:	93 kDa
Description:	This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family.
Further Information:	Immunogen Region: Recombinant human ADAM17 (TACE) ectodomain tagged to biotin. Protein A/G-affinity purified.
Synonym:	CD156B Antibody \| CSVP Antibody \| ADAM18 Antibody \| ADAM metallopeptidase domain 17 Antibody \| TACE Antibody \| NISBD Antibody
NCBI EntrezGene:	6868
Shipping Conditions:	Ship on cold packs
Storage:	Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4 C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Usage:	Research use only

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D1(A12) IgG inhibits constitutive shedding of TNF-? from IGROV1 (human ovarian cancer cell line) into culture medium. Medium was collected after 48 hours of incubation with or without IgGs at 200nM.