Applications: | SDS-PAGE |
Species Reactivity: | Human |
MW: | 11.3kDa (94aa), confirmed by MALDI-TOF. |
Purity: | > 95% by SDS - PAGE |
Description: | CKS2, also known as CDC28 Protein kinase 2 associates with the catalytic subunit of cyclin-dependent kinases and has therefore been assumed to play a direct role in cell cycle regulation. The function of CKS2 in somatic mammalian cells is not well understood although it is required for the first metaphase/anaphase transition during the meiosis. Emerging evidence shows that elevated expression of CKS2 protects the cells from apoptosis. Recombinant CKS2 fused with T7-tag was expressed in E. coli and purified by conventional chromatography techniques. |
Further Information: | Sequence: MASMTGGQQM GRGSHMAHKQ IYYSDKYFDE HYEYRHVMLP RELSKQVPKT HLMSEEEWRR LGVQQSLGWV HYMIHEPEPH ILLFRRPLPK DQQK |
Synonym: | Cyclin-dependent kinases regulatory subunit 2, CKSHS2, CDC28 Protein kinase 2, Cyclin-dependent kinases regulatory subunit 2, CKS2, Cyclin-dependent kinases regulatory subunit 2 CDC28 protein kinase regulatory subunit 2, CKS 2, CKS1(S, cerevisiae Cdc28/Cdc2 kinase subunit) homolog 2, Cyclin dependent kinases regulatory subunit 2. |
Ascension Number: | P33552 |
NCBI EntrezGene: | NP_001818 |
Shipping Conditions: | Ship on cold packs |
Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Usage: | Research use only |