| Applications: | SDS-PAGE |
| Species Reactivity: | Human |
| MW: | 44.4Da (378aa), confirmed by MALDI-TOF. |
| Purity: | > 95% by SDS - PAGE |
| Description: | CDC37, an essential gene in Saccharomyces cerevisiae, interacts genetically with multiple protein kinases. Cdc37 associates with the heat-shock protein 90 (Hsp90) molecular chaperone as one of several auxiliary proteins that are collectively referred to as Hsp90 co-chaperones. Cdc37 up-regulation is a common early event in some localized human cancers. Recombinant CDC37 protein was expressed in E. coli and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: MVDYSVWDHI EVSDDEDETH PNIDTASLFR WRHQARVERM EQFQKEKEEL DRGCRECKRK VAECQRKLKE LEVAEGGKAE LERLQAEAQQ LRKEERSWEQ KLEEMRKKEK SMPWNVDTLS KDGFSKSMVN TKPEKTEEDS EEVREQKHKT FVEKYEKQIK HFGMLRRWDD SQKYLSDNVH LVCEETANYL VIWCIDLEVE EKCALMEQVA HQTIVMQFIL ELAKSLKVDP RACFRQFFTK IKTADRQYME GFNDELEAFK ERVRGRAKLR IEKAMKEYEE EERKKRLGPG GLDPVEVYES LPEELQKCFD VKDVQMLQDA ISKMDPTDAK YHMQRCIDSG LWVPNSKASE AKEGEEAGPG DPLLEAVPKT GDEKDVSV |
| Synonym: | Cell division cycle 37 homolog, P50CDC37, CDC37, Cell division cycle 37 homolog, Cell division cycle 37 homolog S cerevisiae hypothetical protein CDC37, CDC 37, CDC37 cell division cycle 37 homolog, Cdc37 homolog, CDC37 protein, Hsp90 chaperone protein kinase targeting subunit, Hsp90 chaperone protein kinase targeting subunit p50Cdc37, Hsp90 co chaperone Cdc37, p50, p50Cdc37. |
| Ascension Number: | Q16543 |
| NCBI EntrezGene: | NP_008996 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
