| Applications: | SDS-PAGE |
| Species Reactivity: | Human |
| MW: | 14 kDa (129 aa), confirmed by MALDI-TOF. |
| Purity: | > 90% by SDS - PAGE |
| Description: | BNP (Brain natriuretic peptide) is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. BNP is a 32 amino acid polypeptide and is co-secreted along with a 76 amino acid N-terminal fragment which is biologically inactive. This protein has biological actions including natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion. It is thought to play a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Recombinant human BNP, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MHPLGSPGSA SDLETSGLQE QRNHLQGKLS ELQVEQTSLE PLQESPRPTG VWKSREVATE GIRGHRKMVL YTLRAPRSPK MVQGSGCFGR KMDRISSSSG LGCKVLRRH |
| Synonym: | Brain natriuretic peptide (type B natriuretic peptide), NPPB, GC-B, Brain natriuretic peptide (type B natriuretic peptide), BNP, Brain natriuretic peptide (type B natriuretic peptide) Gamma brain natriuretic peptide, Natriuretic peptide precursor B, Natriuretic peptides B, |
| Ascension Number: | P16860 |
| NCBI EntrezGene: | NP_002512 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
