| Applications: | FC, Functional, ELISA |
| Isotype: | Mouse |
| Purification: | PBS, 0.1% BSA, 0.05% azide |
| Conjugation: | Biotin |
| Description: | Recognizes the D1 domain of an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (Leucocyte Workshop VI). CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb is excellent for staining of formalin/paraffin tissues.Primary antibodies are available purified, or with a selection of fluorescent CF� Dyes and other labels. CF� Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF�405S and CF�405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. |
| Further Information: | Flow, surface (published)|Functional studies (published)|ELISA (published) |
| Shipping Conditions: | Ship at ambient |
| Storage: | Store at 4 C |
| Usage: | Research Use Only |
