| Applications: | FC, Functional, IHC(p), ELISA, IP, WB |
| Isotype: | Mouse |
| Purification: | PBS, 0.1% BSA, 0.05% azide |
| Conjugation: | Biotin |
| Description: | Selectins, also designated CD62 antigens, comprise a family of carbohydrate-binding proteins involved in mediating cellular interactions with leukocytes. L-Selectin (also designated LECAM-1 or CD62L) is expressed on the majority of B and naive T cells and on most monocytes, neutrophils and eosinophils. L-Selectin interacts with specific carbohydrates expressed by activated endothelial cells. P-Selectin (also designated GMP-140 or CD62P), expressed on activated platelets and endothelial cells, and E-Selectin (also designated ELMA-1 or CD62E), expressed on endothelial cells, exhibit overlapping ligand specificities. Both recognize sialyl-Le (x) as a ligand and bind to specific carbohydrates on neutrophils and monocytes. Primary antibodies are available purified, or with a selection of fluorescent CF� Dyes and other labels. CF� Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF�405S and CF�405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors. |
| Further Information: | Flow, surface (published)|Functional studies (published)|IHC, FFPE (published)|ELISA (published)|IP (published)|WB (published) |
| Shipping Conditions: | Ship at ambient |
| Storage: | Store at 4 C |
| Usage: | Research Use Only |
