| Applications: | FC, Functional, IF |
| Isotype: | Mouse |
| Purification: | PBS, 0.1% BSA, 0.05% azide |
| Conjugation: | CF568 |
| Description: | CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease. |
| Further Information: | Flow (verified)|Flow, surface (published)|Functional studies (published)|IF (published)|IF (verified) |
| Shipping Conditions: | Ship at ambient |
| Storage: | Store at 4 C |
| Usage: | Research Use Only |
