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Ordering Details

Cat Number:BNC040310-500
Size:500uL
Concentration:0.1 mg/mL
Price:£580.00
Quantity:
Shipping:£12.00

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Data Sheet
MSDS

 

CD7 [B-F12] CF405S, Mouse Monoclonal Antibody

Partner: Biotium

Applications:Functional
Isotype:Mouse
Purification:PBS, 0.1% BSA, 0.05% azide
Conjugation:CF405S
Description:Recognizes a protein of 40 kDa, identified as CD7 (also known as gp40, Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.Primary antibodies are available purified, or with a selection of fluorescent CF� Dyes and other labels. CF� Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF�405S and CF�405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Further Information:Functional studies (published)
Shipping Conditions:Ship at ambient
Storage:Store at 4 C
Usage:Research Use Only

 

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