| Applications: | SDS-PAGE |
| Species Reactivity: | Canine |
| MW: | 15.3kDa (136aa) |
| Purity: | > 95% by SDS - PAGE |
| Description: | IL31, also known as interleukin-31, is a cytokine with an anti-parallel four-helix bundle structure in the gp130/IL-6 cytokine family. It shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. This protein is mainly associated with activated T cells and is preferentially expressed by type 2 helper T cells (Th2). This protein is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. Recombinant Canine IL31 was expressed in insect cell and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: SHMAPTHQLP PSDVRKIILE LQPLSRGLLE DYQKKETGVP ESNRTLLLCL TSDSQPPRLN SSAILPYFRA IRPLSDKNII DKIIEQLDKL KFQHEPETEI SVPADTFECK SFILTILQQF SACLESVFKS LNSGPQ |
| Synonym: | IL31, IL-31, Interleukin-31, Interleukin 31 |
| Ascension Number: | C7G0W1 |
| NCBI EntrezGene: | NP_001159386 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
