| Applications: | Bioactivity, SDS-PAGE |
| Species Reactivity: | Human |
| MW: | 35.9kDa (310aa);;40-57kDa (SDS-PAGE under reducing conditions) |
| Purity: | > 90% by SDS - PAGE |
| Description: | CSF2RA, also known as granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform g, is a well-known hemopoietic growth factor that is used in the clinic to correct neutropaenia, usually as a result of chemotherapy. It is a key regulatory molecule causative of this aortopathy, and modulation of this cytokine might be an exploitable treatment strategy for the condition. It transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Recombinant human CSF2RA, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: ADPLIPEKSD LRTVAPASSL NVRFDSRTMN LSWDCQENTT FSKCFLTDKK NRVVEPRLSN NECSCTFREI CLHEGVTFEV HVNTSQRGFQ QKLLYPNSGR EGTAAQNFSC FIYNADLMNC TWARGPTAPR DVQYFLYIRN SKRRREIRCP YYIQDSGTHV GCHLDNLSGL TSRNYFLVNG TSREIGIQFF DSLLDTKKIE RFNPPSNVTV RCNTTHCLVR WKQPRTYQKL SYLDFQYQLD VHRKNTQPGT ENLLINVSGD LENRYNFPSS EPRAKHSVKI RAADVRILNW SSWSEAIEFG SDDGHHHHHH |
| Synonym: | Granulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform g, CSF2RA, CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM-CSF-R-alpha, GMCSFR, GMR, SMDP4, alphaGMR |
| Ascension Number: | P15509 |
| NCBI EntrezGene: | NP_001155003 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
