| Applications: | SDS-PAGE |
| Species Reactivity: | Mouse |
| MW: | 12.8 kDa (118aa) Confirmed by MALDI-TOF |
| Purity: | > 90% by SDS-PAGE |
| Description: | Vamp2, also known as Vesicle-associated membrane protein 2, is involved in the targeting and/or fusion of transport vesicles to their target membrane. It modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1. Vamp2 proteins localized to the cytoplasmic surface of synaptic vesicle, consists of a proline-rich N-terminal region, a highly conserved hydrophilic domain, followed by a transmembrane anchor and a C-terminal. This proteins also known to mediate cAMP-stimulated exocytosis in nerve cells and in renal cells of the juxtaglomerular apparatus. Recombinant mouse Vamp2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMSATAA TVPPAAPAGE GGPPAPPPNL TSNRRLQQTQ AQVDEVVDIM RVNVDKVLER DQKLSELDDR ADALQAGASQ FETSAAKLKR KYWWKNLK |
| Synonym: | Vesicle-associated membrane protein 2, Syb-2, Syb2, sybII |
| Ascension Number: | P63044 |
| NCBI EntrezGene: | NP_033523 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
