| Applications: | SDS-PAGE |
| Species Reactivity: | Rat |
| MW: | 39.2kDa (356aa);;40-57kDa (SDS-PAGE under reducing conditions) |
| Purity: | > 85% by SDS - PAGE |
| Description: | Il11ra1, also known as interleukin-11 receptor subunit alpha, is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. It can utilize IL6ST for initiating signal transmission. It is expressed in a number of cell lines, including the myelogenous leukemia cell line K562, the megakaryocytic leukemia cell line Mo7E, the erythroleukemia cell line TF1, and the osteosarcoma cell lines, MG-63 and Saos-2. It is also expressed in normal and malignant prostate epithelial cell lines. Recombinant rat Il11ra1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: TPCPQAWGPP GVQYGQPGRP VMLCCPGVNA GTPVSWFRDG DSRLLQGPDS GLGHRLVLAQ VDSRDEGTYV CRTLDGVFGG MVTLKLGSPP ARPEVSCQAV DYENFSCTWS PGRVSGLPTR YLTSYRKKTL PGAESQRESP STGPWPCPQD PLEASRCVVH GAEFWSEYRI NVTEVNPLGA STCLLDVRLQ RILRPDPPQG LRVESVPGYP RRLHASWTYP ASWRRQPHFL LKFRLQYRPA QHPAWSTVEP IGLEELITDA VAGLPHAVRV SARDFLDAGT WSAWSPEAWG TPSTGPLRDE VPDGSRGHEQ KLEAAAQEDS PAPPSPSLQP DPRPLDHRDP LEQVAVLAVE HHHHHH |
| Synonym: | Interleukin-11 receptor subunit alpha, Il11ra1, CRSDA, hCG_2011440, I11RA_HUMAN, IL-11 receptor subunit alpha, IL-11R subunit alpha, IL-11R-alpha, IL-11RA, IL11RA, Interleukin 11 receptor alpha, Interleukin 11 receptor alpha chain, Interleukin-11 receptor subunit alpha, MGC2146 |
| Ascension Number: | Q99MF4 |
| NCBI EntrezGene: | NP_620816 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
