| Applications: | SDS-PAGE |
| Species Reactivity: | Human |
| MW: | 28.2kDa (248aa);;28-40kDa (SDS-PAGE under reducing conditions) |
| Purity: | > 95% by SDS - PAGE |
| Description: | TACSTD1, also known as tumor-associated calcium signal transducer 1, is a membrane glycoprotein expressed on adenomatous and simple epithelia, where it is involved in homophilic adhesion at the basolateral membrane. It may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. It plays a role in embryonic stem cells proliferation and differentiation. Recombinant human TACSTD1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: QEECVCENYK LAVNCFVNNN RQCQCTSVGA QNTVICSKLA AKCLVMKAEM NGSKLGRRAK PEGALQNNDG LYDPDCDESG LFKAKQCNGT STCWCVNTAG VRRTDKDTEI TCSERVRTYW IIIELKHKAR EKPYDSKSLR TALQKEITTR YQLDPKFITS ILYENNVITI DLVQNSSQKT QNDVDIADVA YYFEKDVKGE SLFHSKKMDL TVNGEQLDLD PGQTLIYYVD EKAPEFSMQG LKHHHHHH |
| Synonym: | TACSTD1, CD326, CO17-1A, EGP, EGP40, Ep-CAM, GA733-2, hEGP-2, KSA, M4S1, MIC18, MK-1, TROP1 |
| Ascension Number: | P16422 |
| NCBI EntrezGene: | NP_002345.1 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
