| Applications: | SDS-PAGE |
| Species Reactivity: | Human |
| MW: | 67.5kDa (600aa);;57-70kDa (SDS-PAGE under reducing conditions) |
| Purity: | > 95% by SDS - PAGE |
| Description: | AFP, also known as alpha-fetoprotein, is a major plasma protein produced by the yolk sac and the liver during fetal development. It is thought to be the fetal form of serum albumin. This protein binds to copper, nickel, fatty acids and bilirubin. The main function of this is to prevent the virilization of female fetuses. As it does not bind estrogen, its function in humans is less clear. Recombinant human AFP, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: ADPRTLHRNE YGIASILDSY QCTAEISLAD LATIFFAQFV QEATYKEVSK MVKDALTAIE KPTGDEQSSG CLENQLPAFL EELCHEKEIL EKYGHSDCCS QSEEGRHNCF LAHKKPTPAS IPLFQVPEPV TSCEAYEEDR ETFMNKFIYE IARRHPFLYA PTILLWAARY DKIIPSCCKA ENAVECFQTK AATVTKELRE SSLLNQHACA VMKNFGTRTF QAITVTKLSQ KFTKVNFTEI QKLVLDVAHV HEHCCRGDVL DCLQDGEKIM SYICSQQDTL SNKITECCKL TTLERGQCII HAENDEKPEG LSPNLNRFLG DRDFNQFSSG EKNIFLASFV HEYSRRHPQL AVSVILRVAK GYQELLEKCF QTENPLECQD KGEEELQKYI QESQALAKRS CGLFQKLGEY YLQNAFLVAY TKKAPQLTSS ELMAITRKMA ATAATCCQLS EDKLLACGEG AADIIIGHLC IRHEMTPVNP GVGQCCTSSY ANRRPCFSSL VVDETYVPPA FSDDKFIFHK DLCQAQGVAL QTMKQEFLIN LVKQKPQITE EQLEAVIADF SGLLEKCCQG QEQEVCFAEE GQKLISKTRA ALGVHHHHHH |
| Synonym: | Alpha-fetoprotein, AFPD, FETA, HPAFP |
| Ascension Number: | P02771 |
| NCBI EntrezGene: | NP_001125 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
