| Applications: | SDS-PAGE |
| Species Reactivity: | Rat |
| MW: | 19.8kDa (175aa) confirmed by MALDI-TOF |
| Purity: | > 90% by SDS - PAGE |
| Description: | Il1rn also known as Interleukin-1 receptor antagonist protein is a member of the interleukin 1 cytokine family. Il1rn may represent a reservoir of IL-1 inhibitors, released upon cell death, whose function is no limit the pro-inflammatory signals but most prominently by mononuclear phagocytes and keratinocytes. Il1rn is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Recombinant rat Il1rn, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MGSHPAGKRP CKMQAFRIWD TNQKTFYLRN NQLIAGYLQG PNTKLEEKID MVPIDFRNVF LGIHGGKLCL SCVKSGDDTK LQLEEVNITD LNKNKEEDKR FTFIRSETGP TTSFESLACP GWFLCTTLEA DHPVSLTNTP KEPCTVTKFY FQEDQ |
| Synonym: | Interleukin-1 receptor antagonist protein, IL-1ra, il1ra |
| Ascension Number: | P25086 |
| NCBI EntrezGene: | NP_071530 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
