| Applications: | SDS-PAGE |
| Species Reactivity: | Human |
| MW: | 15.1kDa (137aa) confirmed by MALDI-TOF. |
| Purity: | > 85% by SDS - PAGE |
| Description: | AGRP, also known as agouti-related protein also called agouti-related peptide, is a neuropeptide produced in the brain by the AGRP/NPY neuron. It is only synthesised in NPY-containing cell bodies located in the ventromedial part of the arcuate nucleus in the hypothalamus. AGRP is co-expressed with Neuropeptide Y and works by increasing appetite and decreasing metabolism and energy expenditure. It is one of the most potent and long-lasting of appetite stimulators. Recombinant human AGRP, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMAQMGL APMEGIRRPD QALLPELPGL GLRAPLKKTT AEQAEEDLLQ EAQALAEVLD LQDREPRSSR RCVRLHESCL GQQVPCCDPC ATCYCRFFNA FCYCRKLGTA MNPCSRT |
| Synonym: | Agouti-related protein, Agouti-related protein, AGRT, ART, ASIP2 |
| Ascension Number: | O00253 |
| NCBI EntrezGene: | NP_001129 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
