| Applications: | SDS-PAGE, Denatured |
| Species Reactivity: | Human |
| MW: | 16.8kDa (152aa) |
| Purity: | > 90% by SDS - PAGE |
| Description: | CCL25 also known as C-C motif chemokine 25 isoform 1. CCL25 is potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. It binds to CCR9. Isoform 2 is an antagonist of isoform1 and binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. Recombinant human CCL25-iso1, fused to His-tag at N-terminus, was expressed in E. coli. |
| Further Information: | Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMQGVFE DCCLAYHYPI GWAVLRRAWT YRIQEVSGSC NLPAAIFYLP KRHRKVCGNP KSREVQRAMK LLDARNKVFA KLHHNTQTFQ AGPHAVKKLS SGNSKLSSSK FSNPISSSKR NVSLLISANS GL |
| Synonym: | C-C motif chemokine 25 isoform 1, Ckb15, SCYA25, TECK |
| Ascension Number: | O15444 |
| NCBI EntrezGene: | NP_005615 |
| Shipping Conditions: | Ship on cold packs |
| Storage: | Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
| Usage: | Research use only |
